MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes

Figure 2

Putative sequences targeted by the miR-29b seed sequence in the 3′-untranslated region (3′-UTR) of human COL1A2 and COL2A1 mRNAs. (a) Predicted duplex formation between miR-29b and 3′-UTRs by the TargetScan algorithm. (b) Cross-species conservation of the targeted sequences in the 3′-UTRs of COL1A2 and COL2A1 mRNAs.

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(b)