Local Anesthetics, Procaine, Lidocaine, and Mepivacaine Show Vasodilatation but No Type 1 Allergy: A Double-Blind, Placebo-Controlled Study

Figure 3

Development of skin reaction: intensity of erythema (0 = none, 1 = light red, and 2 = dark red) with error bars following intracutaneous injection with three different LAs and 0.9% saline solution in 340 tests. Description was documented after 1, 2, 5, 10, and 15 minutes, respectively.