RNA-seq Based Transcription Characterization of Fusion Breakpoints as a Potential Estimator for Its Oncogenic Potential

Figure 2

The dot-scatter plot comparison of the number of fusion reads and the overlapping reads. Diagram (a) shows fusion mutations in cell line samples. Diagram (b) shows fusion mutations in primary tumor and normal tissue samples. The green, blue, and black dots in diagram (b) represent normal counterparts, tumor, and recurrent fusion mutations, respectively. Dots give an observational estimate that fusion mutations occurring in tumors and normal tissues have more normal overlapping reads than in cancer cell lines.

(a)

(b)