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BioMed Research International
Volume 2017, Article ID 9829175, 8 pages
Research Article

RNA-seq Based Transcription Characterization of Fusion Breakpoints as a Potential Estimator for Its Oncogenic Potential

Jian-lei Gu,1,2,3 Morris Chukhman,4 Yao Lu,1,2 Cong Liu,1,2,4 Shi-yi Liu,2 and Hui Lu1,2,3,4

1Shanghai Institute of Medical Genetics, Shanghai Children’s Hospital, Shanghai Jiao Tong University, Shanghai 200040, China
2Department of Bioinformatics, SJTU-Yale Joint Center for Biostatistics, Shanghai Jiao Tong University, Shanghai 200240, China
3Key Laboratory of Molecular Embryology, Ministry of Health and Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai 200040, China
4Department of Bioengineering, Bioinformatics Program, University of Illinois at Chicago, Chicago, IL 60607, USA

Correspondence should be addressed to Hui Lu; moc.liamg@ofnioib.uliuh

Received 21 December 2016; Accepted 23 August 2017; Published 17 October 2017

Academic Editor: Ansgar Poetsch

Copyright © 2017 Jian-lei Gu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Figure S1: The boxplot comparison of iFCRmax values among four groups.

Figure S2: The boxplot comparison of iFCRmin values among four groups.

Figure S3: The comparison of fold changes of parents’ genes and iFCR value (x-axis).

  1. Supplementary Material