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BioMed Research International
Volume 2017, Article ID 9840210, 11 pages
https://doi.org/10.1155/2017/9840210
Research Article

Evidence for Tissue Toxicity in BALB/c Exposed to a Long-Term Treatment with Oxiranes Compared to Meglumine Antimoniate

1Laboratório de Biologia Molecular e Doenças Endêmicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Avenida Brasil 4365, Manguinhos, 21040-900 Rio de Janeiro, RJ, Brazil
2Laboratório de Imunoparasitologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (Fiocruz), Avenida Brasil 4365, Manguinhos, 21040-900 Rio de Janeiro, RJ, Brazil
3Laboratório de Ultraestrutura e Biologia Tecidual, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro, Boulevard 28 de Setembro, No. 87, Vila Isabel, 20551-030 Rio de Janeiro, RJ, Brazil
4Laboratório de Tecnologia Virológica, Instituto de Tecnologia em Imunobiológicos, Fundação Oswaldo Cruz (Fiocruz), Avenida Brasil 4365, Manguinhos, 21040-900 Rio de Janeiro, RJ, Brazil
5Instituto de Biologia, Universidade Federal Fluminense, Outeiro São João Batista S/N, 24210-130 Niterói, RJ, Brazil
6Departamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Outeiro São João Batista S/N, Centro, 24210-130 Niterói, RJ, Brazil
7Laboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Avenida Brasil 4365, Manguinhos, 21040-900 Rio de Janeiro, RJ, Brazil

Correspondence should be addressed to Carlos Roberto Alves; rb.zurcoif.coi@sevlac

Received 3 March 2017; Revised 19 May 2017; Accepted 1 June 2017; Published 17 July 2017

Academic Editor: Philippe Holzmuller

Copyright © 2017 Luiz Filipe Gonçalves Oliveira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [1 citation]

The following is the list of published articles that have cited the current article.

  • Luiz Oliveira, Franklin Souza-Silva, Luzia de Castro Côrtes, Lea Cysne-Finkelstein, Mirian de Souza Pereira, Francisco de Oliveira Junior, Rosa Pinho, Suzana Corte Real, Saulo Bourguignon, Vitor Ferreira, and Carlos Alves, “Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2′-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment,” Molecules, vol. 23, no. 4, pp. 864, 2018. View at Publisher · View at Google Scholar