Advances and Current Concepts in the Medical Management of Gastroenteropancreatic Neuroendocrine Neoplasms

Table 2

Factors that need to be considered in order to select the most appropriate treatment along with currently available nonsurgical treatments for pancreatic neuroendocrine neoplasms.

Tumor-related factors
Functioning tumor		SS-analogs; Chemotherapy; Molecular targeted; therapy; Liver-directed therapy; PRRT
Grading
Extent of disease (liver or other metastases)
Extent of liver involvement
Tumor growth rate
SRS uptake
Patient-related factors
Patient performance status
Presence of a familial syndrome
Patient’s preference
Health-economy-related factors
Local availability

SRS: somatostatin receptor scintigraphy; SS: somatostatin; PRRT: peptide receptor radionuclide therapy.