Pterostilbene Induces Cell Apoptosis and Cell Cycle Arrest in T-Cell Leukemia/Lymphoma by Suppressing the ERK1/2 Pathway

Figure 4

Pterostilbene induces MMP decline and ROS generation in T-cell leukemia/lymphoma cells. (a) Pterostilbene treatment (0, 20, 40, and 80 μM) for 48 h induced mitochondrial depolarization in Jurkat and Hut-78 cells. Data were shown as mean ± SD, . , compared to the control group. (b) Jurkat and Hut-78 cells treated with pterostilbene (0, 10 μM) for 48 h by flow cytometry. In the negative group, Jurkat and Hut-78 cells were treated without pterostilbene and DCFH-DA. Data were shown as mean ± SD, . , compared to the control group.

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