Discovering Associations of Adverse Events with Pharmacotherapy in Patients with Non-Small Cell Lung Cancer Using Modified Apriori Algorithm

Table 6

Meaningful association rules between adverse events and drugs.

Adverse event	Drug	Comp	Support	Confidence
Anemia	Cisplatin	26.897	0.174	61.426
Activated partial thromboplastin time prolonged	Meropenem	15.757	0.036	36.500
Alanine aminotransferase increased	Pemetrexed	21.411	0.162	46.197
Alkaline phosphatase increased	Zoledronic acid	20.635	0.043	28.212
Aspartate aminotransferase increased	Pemetrexed	16.549	0.162	32.327
Blood bilirubin increased	Folium Sennae	8.834	0.196	31.459
Cholesterol high	Cisplatin	13.373	0.170	37.834
GGT increased	Cisplatin	16.731	0.172	45.753
Hemoglobin increased	Lentinan	4.793	0.235	25.064
Neutrophil count decreased	Cisplatin	46.431	0.173	61.619
Platelet count decreased	Gemcitabine	25.428	0.051	37.470
White blood cell decreased	Cisplatin	39.577	0.173	62.929
Hyperglycemia	Diprophylline	12.320	0.038	63.535
Hypermagnesemia	Pazufloxacin	17.857	0.015	38.889
Hypertriglyceridemia	Cisplatin	16.980	0.170	56.539
Hyperuricemia	Cisplatin	11.228	0.168	29.501