Rapid-Onset Obesity with Hypoventilation, Hypothalamic, Autonomic Dysregulation, and Neuroendocrine Tumors (ROHHADNET) Syndrome: A Systematic Review
Table 4
Laboratory findings of patients with ROHHADNET syndrome (IPD).
Laboratory findings
Total number of patients (n=48)
Number of patients ()
ABGA
Hypoxemia
13/13(100%)
Hypercapnia
14/15 (93.3%)
Normal
0/15 (0%)
No information
34/48 (70.8%)
Dysnatremia
Hypernatremia
25/31 (80.6%)
Hyponatremia
5/31 (16.1%)
Normal
2/31 (6.5%)
No information
17/48(35.4%)
Prolactin
Hyperprolactinemia
27/28 (96.4%)
Normal
1/28 (3.6%)
No information
19/48 (39.6%)
Thyroid dysfunction
Hypothyroidism
18/30 (60.0%)
Normal
12/30 (40.0%)
No information
17/48 (35.4%)
IGF-1 level
Low
12/16 (75.0%)
Normal
4/16 (25.0%)
No information
31/48 (64.6%)
ABGA: Arterial blood gas analysis, IGF-1: Insulin-like growth factor-1. Hypoxemia is defined in terms of reduced partial pressure of oxygen below 80 mmHg or decreased oxygen saturation less than 90%. Hypercapnia is defined in terms of elevated carbon dioxide above 45 mmHg.
