The Influence of Formulation and Excipients on Propranolol Skin Permeation and Retention

Figure 1

Permeation profiles of propranolol from semisolid formulations (–●– ointment1; –○– ointment2; –■– cream1; –□– cream2; –◆– poloxamer 407 gel) across intact (Panel a) and stripped isolated epidermis (Panel b). Mean values ± sd.

(a)

(b)