Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice

Table 3

Hormone profile of CD1 mice supplemented with sweeteners for 12 weeks.

	Baseline (3rd week)	Middle (9th week)				Final (15th week)
		CL	SUC	SUCL	ST	CL	SUC	SUCL	ST
	Mean ± SD	Median ± SD	Median ± SD	Median ± SD	Median ± SD	Median ± SD	Median ± SD	Median ± SD	Median ± SD
GIP	123.2	37.14	66.57	75.59	86.59	127	121	93	145
Insulin	545.9	260	196	602		938	1143	939
Leptin	275.5	245	181	187	456	380	459	446	421
HOMA Index	181.4	340	132	240		456	390	396

The values represent the median in pg/mL for each determination; a nonparametric Kruskal-Wallis was made of independent samples to compare the differences between the subgroups: the differences were considered significant with a value < . CL = Control, SUC = Sucrose, SUCL = Sucralose, and ST = Stevia.