Research Article

Drug-Target Interaction Prediction via Dual Laplacian Graph Regularized Matrix Completion

Table 1

The statistics of drugs, targets, and interactions in each dataset.

Datasets NRs GPCRs ICs Es DB

Drugs 54 223 210 445 1936
Targets 26 95 204 664 1609
Interactions 90 635 1476 2926 7019
Average No. of drugs per target 3.466.68 7.24 4.41 4.36
Average No. of targets per drug1.672.85 7.03 6.58 3.63
Sparsity of the interaction matrix (%)93.5997.00 96.55 99.01 99.77
Percentage of drugs with only one interaction target (%)72.2247.53 38.57 39.78 75.20
Percentage of targets with only one interaction drug (%)30.7735.7911.2743.3730.53