In Vivo Study of the Effects of ER on Apoptosis and Proliferation of Hormone-Independent Prostate Cancer Cell Lines PC-3M

Figure 4

Representative photographs from western blot assay of tumor tissues from the PQ-v and PQ- ERβ groups, and quantification of these genes at the protein level. (a) The expression of ER; (b) the expression of Akt and p-Akt; (c) the expression of p-caspase 9, p-caspase 3, and PARP; (d) the expression of Bad and Bcl-xl in the PQ-v and PQ-ERβ groups. PQ-v: PQ-PCDNA3.1 group; PQ-ERβ: PQ-PCDNA3.1-ERβ group. indicates that apoptosis induced by PQ-PCDNA3.1-ERβ was significantly greater than that in the MOCK, PQ, and PQ-PCDNA3.1 groups ().

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