Health-Related Quality of Life among Women Breast Cancer Patients in Eastern China

Table 3

Quality of life scores (mean ± SD) by TNM stage, type of treatment.

EORTC Items	TNM stage				P	Type of treatment		P
	0-I	II	III	IV		Chemotherapy only	Others
Panel A: QLQ-C30 Questionnaire
GHS	55.1±13.3	54.0±15.8	52.6±15.1	53.9±14.0	0.497	51.8±12.8	55.6±15.9	<0.001
Functional scales
PF	75.5±17.2	78.5±15.1	74.4±18.0	73.0±18.4	0.068	78.5±16.2	72.8±17.7	<0.001
RF	76.9±25.0	81.1±25.2	76.2±25.4	74.4±27.5	0.112	81.0±23.3	74.1±27.0	0.001
EF	75.0±18.3	77.0±19.5	72.3±20.6	72.7±20.3	0.170	75.9±18.7	72.7±20.5	0.052
CF	78.2±18.1	79.2±17.4	74.8±21.8	75.3±18.7	0.303	79.0±18.3	74.9±20.3	0.012
SF	71.5±25.8	71.8±22.8	68.6±25.3	66.2±22.6	0.180	71.5±23.5	68.5±25.5	0.118
Symptom scales
FA	34.4±16.4	30.9±18.3	35.0±18.5	36.2±19.8	0.017	32.0±16.1	35.8±19.5	0.016
NV	19.5±21.2	14.0±18.6	20.9±23.2	21.7±20.7	0.010	15.0±19.1	22.6±22.8	<0.001
DI	10.5±18.2	7.5±16.1	12.2±21.5	10.5±16.5	0.211	7.5±16.0	13.0±20.8	0.001
FI	33.9±31.0	33.6±28.0	35.0±27.6	37.4±27.7	0.568	33.6±26.8	35.6±30.2	0.545
PA	29.4±18.8	25.0±19.5	30.3±20.6	30.8±20.0	0.025	26.1±18.7	31.3±20.5	0.001
DY	17.9±21.7	12.2±18.0	19.1±23.7	19.6±25.4	0.039	12.7±19.3	21.2±23.9	<0.001
SL	32.2±24.2	26.8±22.5	32.7±24.6	34.7±26.9	0.092	30.2±24.1	32.5±24.6	0.225
AP	23.6±23.4	18.3±23.0	26.6±26.7	28.8±27.9	0.009	21.5±23.4	26.3±26.7	0.038
CO	26.5±26.6	19.0±23.3	26.6±28.0	25.1±25.3	0.048	23.0±26.1	26.0±26.6	0.136
Panel B: QLQ-BR23 Questionnaire
Functional scales
BRBI	65.2±24.3	67.6±26.4	62.9±24.8	64.8±24.4	0.355	65.9±25.9	64.0±24.2	0.090
BRSEF	87.1±16.5	91.1±15.7	89.2±15.7	88.6±15.2	0.081	92.4±14.0	85.9±16.9	<0.001
BRFU	51.0±31.5	53.5±33.9	49.7±30.9	53.9±27.6	0.600	51.4±30.8	51.6±32.0	0.902
BRSEE	87.5±18.1	91.2±17.8	87.6±21.6	87.2±19.7	0.153	92.8±14.6	84.3±22.4	<0.001
Symptom scales
BRST	24.8±16.2	21.8±15.7	26.5±17.8	24.8±17.1	0.097	23.0±15.6	26.3±17.8	0.023
BRBS	17.1±18.6	13.2±16.9	18.6±21.5	20.3±21.8	0.075	14.6±19.5	19.4±19.8	<0.001
BRAS	20.4±18.4	17.2±18.5	20.7±20.8	24.2±20.6	0.083	17.8±19.6	22.4±19.4	0.001
BRHL	38.6±30.5	37.8±32.1	40.3±29.9	34.7±27.3	0.562	39.7±30.3	37.6±30.3	0.450

SD, standard deviation.
GHS, global health status; PF, physical functioning; RF, role functioning; EF, emotional functioning; CF, cognitive functioning.
SF, social functioning; FA, fatigue; NV, nausea and vomiting; DI, diarrhoea; FI, financial difficulties; PA, pain; DY, dyspnoea.
SL, insomnia; AP, appetite loss; CO, constipation; BRBI, body image; BRSEF, sexual functioning; BRFU, future perspective.
BRSEE, sexual enjoyment; BRST, systemic therapy side effect; BRBS, breast symptoms; BRAS, arm symptoms; BRHL, upset by hair loss.