A Novel<i> MLH1</i> Initiation Codon Mutation (c.3G>T) in a Large Chinese Lynch Syndrome Family with Different Onset Age and mRNA Expression Level

<div>The relative mRNA level of MLH1 in these family members with or without MLH1 mutation. III:1, II:2, and III:3 are patients, II:5, IV:1, and IV:4 are unaffected carriers, III:5 and II:1 are non-carriers in this family, and normal control is a non-carrier of MMRs gene with no blood relationship to this family. The levels of MLH1 in patients were lower than those with wild type MLH1 or unaffected carriers.</div>

BioMed Research International

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Figure 4: A Novel<i> MLH1</i> Initiation Codon Mutation (c.3G>T) in a Large Chinese Lynch Syndrome Family with Different Onset Age and mRNA Expression Level 

Figure 4 | A Novel MLH1 Initiation Codon Mutation (c.3G>T) in a Large Chinese Lynch Syndrome Family with Different Onset Age and mRNA Expression Level 