Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges

Table 7

Comparison of the kidney development among species.

Glomerular nephrogenesis			GFR	Concentrating ability
species	onset	completion	age	age
Human	GD 35-37	35 weeks of gestation	1-2 years	1 year
Rat	GD12.5	Postnatal weeks 4-6	6 wk	6 wk
Mouse	GD11	Before birth	nr	nr

time when adult levels are reached. GD: gestation day; GFR: glomerular filtration rate. Data from Zoetis et al. [153].