Transcriptional Profiling of Leucocyte Count Variation from Porcine Peripheral Blood Reveals Differential Gene Expression

Table 2

Major functional annotation clusters in poly I:C-induced leucocyte responders based on fold change (FC) and (p < 0.01).

GO name	Gene count	Fold change	Genes
			Expressed in increased leucocyte responders	Expressed in decreased leucocyte responders
Innate immunity	10	18.20	DDX58, SH2D1A, CFB, RSAD2, TLR4, S100A12, ISG20	DDX58, CFB, RSAD2, TLR4, OAS1, MX1, MX2, ISG20
Innate immune response	14	7.18	DDX58, SH2D1A, S100A8, S100A9, RSAD2, TLR4, TNK2, S100A12, ISG20	DDX58, PTK2B, TRIM26, RSAD2, TLR4, OAS1, MX2, ISG20, TEC
Immunity	10	10.76	DDX58, SH2D1A, CFB, RSAD2, TLR4, S100A12, ISG20	DDX58, CFB, RSAD2, TLR4, OAS1, MX1, MX2, ISG20
Negative regulation of viral genome replication	6	22.47	-	PLSCR1, ISG15, RSAD2, OAS1, MX1, ISG20
Defense response to virus	9	6.68	IFIT3, PLSCR1, IFIT2, ISG15, RSAD2, OAS1, MX1, MX2, ISG20	PLSCR1, ISG15, RSAD2, OAS1, MX1, ISG20
Antiviral defense	6	9.10	DDX58, RSAD2, ISG20	DDX58, RSAD2, OAS1, MX1, MX2, ISG20