Transcriptome Analysis Reveals Dynamic Gene Expression Profiles in Porcine Alveolar Macrophages in Response to the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

Figure 2

Gene expression profiles distinguishing different groups. Shown is the volcano plot of differentially expressed genes between each comparison group, including the mRNAs between and (a), and (b), and (c), and (d), and and (e), the annotated lncRNAs between and (f), and (g), and (h), and (i), and and (j), and the novel lncRNAs between and (k), and (l), and (m), and (n), and and (o). Red dots denote the expressed genes with a greater than 2-fold expression change and FDR-corrected value < 0.05. Black dots denote the genes that were expressed comparably in comparison groups. (p, q, r) Unsupervised hierarchical clustering of the expression profiles of differentially expressed mRNAs, annotated lncRNAs, and novel lncRNAs with the same change trend in PRRSV-infected groups in comparison to mock-infected groups, respectively.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)

(k)

(l)

(m)

(n)

(o)

(p)

(q)

(r)