Research Article

Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs

Table 2

Distribution of the cochleas from the 5 experimental groups among the three histological categories and corresponding averages.

Category 1N1Category 2N2Category 3N3
No OHC and SGC lossOHC loss only Both OHC and SGC loss

Group II4Group I1Group I1

Group III4Group II2Group II2

Group IV4

Group V2

Total1433

OHC loss0%46.0 ± 5.7%68.3 ± 6.9%

SGC loss4.7 ± 3.0%10.8 ± 6.0%49.4 ± 4.3%

Threshold shift1.7 ± 11.9 dB44.9 ± 2.7 dB39.0 ± 2.4 dB

Amplitude3.8 ± 5.0 dB17.1±3.8 dB15.8 ± 1.6 dB