Matrix Metalloproteinase-9 Is a Predictive Factor for Systematic Hypertension and Heart Dysfunction in Patients with Obstructive Sleep Apnea Syndrome
Table 4
Risk factors of hypertension occurrence in OSAS patients.
Cases
DFS Months
value
Age, year
≤55
20
0.429
>55
15
Gender,
Male
26
0.448
Female
9
BMI, kg/m2
≤23.9
8
0.787
>23.9
27
Neck circumference, cm
≤42.3
19
0.204
>42.3
16
Waist circumference, cm
≤119.0
18
0.269
>119.0
17
OSAS severity
Mild
13
0.010
Moderate and severe
22
ODI
≤22
19
0.066
>22
16
ESS
≤9
19
0.869
>9
16
Lowest SpO2, %
≤82
18
0.028
>82
17
Mean SpO2, %
≤91
19
0.259
>91
16
Time of SpO2 < 90%, min
≤10
18
0.074
>10
17
Systolic BP, mm Hg
≤114
18
0.333
>114
17
Diastolic BP, mm Hg
≤76
18
0.660
>76
17
Heart rate
≤63
18
0.123
>63
17
MMP-9 level, ng/mL
≤143
19
0.006
>143
16
All cut-off values are median values, except for BMI (BMI = 23.9 is the cut-off value for normal and obese); by Student’s -test; BMI: body mass index; AHI: apnea/hypopnea index; ODI: oxygen desaturation index; ESS: Epworth sleepiness scale; SpO2: blood oxygen saturation; BP: blood pressure.
