Role of MAPKs in HSP70’s Protection against Heat Stress-Induced Injury in Rat Small Intestine

Figure 4

Effects of HSP70 inhibition on the intestinal integrity and function of heat stressed rats. The experiment lasted for 14 days with daily 50 min of heat stress treatment (43°C) for the HS and HQ groups. Rats of HQ group were intragastrically given 0.5 mL quercetin solution (50 mg/kg body weight) before the heat stress treatment. (a) D-lactate and (b) diamine oxidase levels were detected by ELISA on days 7 and 14 after heat stress. Data are shown as mean ± standard error of mean (SEM) (n=8). The values with different letters (A, B) are significantly different (P<0.05). CON: control; HS: heat stress; HQ: heat stress + quercetin.

(a)

(b)