Role of MAPKs in HSP70’s Protection against Heat Stress-Induced Injury in Rat Small Intestine

Figure 6

Effects of HSP70 inhibition on the activation of caspase-3 in the jejunal mucosa of heat stressed rats. The experiment lasted for 14 days with daily 50 min of heat stress treatment (43°C) for the HS and HQ groups. Rats of HQ group were intragastrically given 0.5 mL quercetin solution (50 mg/kg body weight) before the heat stress treatment. Western blotting was used to detect the protein levels of procaspase-3 and cleaved caspase-3. (a) On day 7 of heat stress. (b) On day 14 of heat stress. Data are shown as mean ± standard error of mean (SEM) (n=6). The values with different letters (A, B, C) are significantly different (P<0.05). CON: control; HS: heat stress; HQ: heat stress + quercetin.

(a)

(b)