Research Article
Pharmacokinetics and Bioavailability Study of Monocrotaline in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
Table 1
The precision, accuracy, recovery, and matrix effect of MCT in mouse blood (n = 6).
| | Concentration (ng/mL) | Precision (RSD%) | Accuracy (%) | Found (ng/mL) | Matrix effect (%) | Recovery (%) | | Intra-day | Inter-day | Intra-day | Inter-day | Intra-day | Inter-day |
| | 3 | 9.6 | 12.6 | 106.6 | 96.6 | 3.2±0.3 | 2.9 ±0.4 | 89.0±7.6 | 81.9 ±6.4 | | 180 | 11.1 | 12.0 | 99.4 | 104.4 | 178.9±19.9 | 187.9 ±22.6 | 94.3±4.5 | 77.2±3.6 | | 1800 | 7.3 | 8.2 | 96.2 | 98.4 | 1731.6±126.4 | 1771.2 ±145.2 | 92.2 ±4.1 | 75.0±4.6 |
|
|
