Research Article
Pharmacokinetics and Bioavailability Study of Monocrotaline in Mouse Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry
Table 2
Summary of stability of MCT under various storage conditions (n = 3).
| | Concentration (ng/mL) | Auto sampler ambient | Ambient 12 h | -20°C 30 d | Freeze-thaw | | Found (ng/mL) | Accuracy (%) | RSD (%) | Found (ng/mL) | Accuracy (%) | RSD (%) | Found (ng/mL) | Accuracy (%) | RSD (%) | Found (ng/mL) | Accuracy (%) | RSD (%) |
| | 3 | 2.9± 0.1 | 96.6 | 3.5 | 3.1 ±0.2 | 102.9 | 7.6 | 2.8±0.4 | 93.6 | 13.8 | 2.7 ±0.3 | 88.9 | 13.0 | | 180 | 183.4±9.7 | 101.9 | 5.3 | 190.8±9.2 | 106.0 | 4.8 | 177.1±20.4 | 98.4 | 11.5 | 162.2 ±8.3 | 90.1 | 5.1 | | 1800 | 1879.2± 54.5 | 104.4 | 2.9 | 1657.8±89.5 | 92.1 | 5.4 | 1936.8 ±108.5 | 107.6 | 5.6 | 1918.8±188.0 | 106.6 | 9.8 |
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