Influence of Adalimumab on the Expression Profile of Genes Associated with the Histaminergic System in the Skin Fibroblasts In Vitro

Table 3

Transcripts of genes associated with the histaminergic system, differentiating the response of adalimumab treatment on NHDF cells, compared with the control samples.

ID	Gene symbol	2 hours; (up/down)	FC; (2 hours versus C)	24 hours; (up/down)	FC; (24 hours versus C)	8 hours; (up/down)	FC; (8 hours versus C)
201557_at	VAMP2	Up	1.3076547	Down	−1.037129	Down	−1.0554649
202625_at	LYN	Down	−1.0955737	Up	1.1316916	Up	1.1089189
204112_s_at	HNMT	Up	1.6368151	Down	−1.1016508	Down	−1.1010625
204463_s_at	EDNRA	Down	−1.226046	Up	1.09312	Up	1.4448898
204464_s_at	EDNRA	Down	−1.2038972	Down	−1.0421386	Up	1.4517964
204639_at	ADA	Up	1.1746593	Down	−1.0697097	Up	1.0407584
205329_s_at	SNX4	Up	1.0058819	Up	1.1812408	Up	1.0806441
205421_at	SLC22A3	Up	1.0740671	Down	−1.0358303	Up	2.274354
206678_at	GABRA1	Down	−1.1993337	Down	−1.282568	Down	−1.0323519
205579_at	HRH1	Up	2.4778538	Up	1.0098535	Down	−1.0161992
205580_s_at	HRH1	Up	2.3650975	Down	−1.0148736	Down	−1.0308013
209190_s_at	DIAPH1	Down	−1.3211001	Down	−1.0192791	Down	−1.082756
211624_s_at	DRD2	Down	−1.0191133	Down	−1.36553	up	1.0382545
211732_x_at	HNMT	Up	1.3924775	Down	−1.0599645	up	1.0668004
218995_s_at	EDN1	Up	1.8715541	Down	−1.0243433	up	1.3998785