Effect of Coenzyme Q₁₀ on Insulin Resistance in Korean Patients with Prediabetes: A Pilot Single-Center, Randomized, Double-Blind, Placebo-Controlled Study

Table 3

Univariate and multiple regression analyses of variables that affect changes in the blood concentration of coenzyme Q10.

Variables		Parameter estimate	P-value	Adjusted r-square
Univariate regression
		-0.0169	.97	-0.0135
Insulin		-0.0039	.56	-0.0089
Oxidative stress		-0.0087	<0.001	0.2860
HOMA-IR		-0.0146	.53	-0.0078
Multitple regression
		0.0023	>.99
Model 1	Insulin	-0.0027	0.64	0.2397
	Oxidative stress	-0.0089	<0.001
		-0.0331	.93
Model 2	Insulin	-0.0308	.12	0.2525
	Oxidative stress	-0.0097	<.001
	HOMA-IR	0.1017	.01

, glycated hemoglobin; HOMA-IR, homeostasis model assessment-insulin resistance.