Gallic Acid Attenuates Dimethylnitrosamine-Induced Liver Fibrosis by Alteration of Smad Phosphoisoform Signaling in Rats

Table 1

Effects of GA on body and organ weight in rats with DMN-induced liver fibrosis (n = 8).

	Weight (g)
Group	Body	Liver	Kidney	Spleen
Group I control	442.38± 16.72 a	15.58±0.90 a	2.85±0.15 a	1.09±0.09 a
Group II DMN	383.08±9.24 bc	12.81±0.45 b	2.44±0.09 b	0.98±0.05 a
Group III silymarin 100 (mg/kg)	368.78±12.94 b	11.66±0.74 b	2.46±0.13 b	0.99±0.07 a
Group IV GA 25 (mg/kg)	399.90±7.14 c	14.01±0.68 ab	2.64±0.10 ab	1.12±0.04 a
Group V GA 50 (mg/kg)	384.88±8.03 bc	12.66±0.45 b	2.47±0.09 b	1.11±0.06 a
Group VI GA 100 (mg/kg)	361.94±10.38 b	12.03±0.40 b	2.45±0.09 b	1.02±0.05 a

Values are Mean ± SEM., “a, b, c” means values in the same column with different letters are significantly different from each other (p<0.05).