Tranexamic Acid for Adults with Melasma: A Systematic Review and Meta-Analysis

Table 3

Assessment of the quality of cohort studies.

Study; (first author, year)	Selection				Comparability	Outcome			Score
	Representativeness of exposed cohort	Selection of nonexposed cohort	Ascertainment of exposure	Demonstration that outcomes^†		Assessment	Enough follow-up	Adequacy of follow-up of cohorts
Kim 2016	☆	-	☆	☆	☆☆	-	☆	☆	7
Lee 2006	☆	-	☆	☆	☆☆	-	☆	-	6
Na 2012	☆	-	☆	☆	☆☆	-	☆	-	6

The assessment was based on the Newcastle-Ottawa Scale. The full mark of total score is defined as 9; a score of >7 indicates a low risk of bias.
†A demonstration about the outcomes of interest was not present initially.