A Novel and Convenient Method for the Preparation and Activation of PRP without Any Additives: Temperature Controlled PRP

Figure 7

Theoretical computer modeling of a t-PRP gel. (a) Theoretical computer modeling of fibrin networks resulting from fibrin glue polymerization. (b-c) Theoretical computer modeling of fibrin networks resulting from c-PRP (b) and t-PRP (c) polymerization. The c-PRP showed that activated platelets are trapped in the fibrin meshes and release GFs extrinsically retained in the fibrin architecture. The t-PRP slow polymerization process would allow the intrinsic retaining of platelet derived GFs within fibrin polymers. (1) Platelet trapped in the fibrin gel. (2) Platelet derived GFs in solution. (c) Fibrin networks resulting from t-PRP polymerization. (3) Platelet derived GFs trapped in fibrin gel.

(a)

(b)

(c)