Evaluation of Lsa46 and Lsa77 Leptospiral Proteins for Their Immunoprotective Activities in Hamster Model of Leptospirosis

Table 3

Effect of immunization with Lsa77 recombinant protein in a hamster model.

Groups	N° Survivors/		N°Survivors/Total	Total	Renal	Renal	Renal
	Total			Survival	Culture	Culture	Culture	Culture
								Positive
					Positive /	Positive /	Positive /
					Total	Total	Total
	Exp.1	Exp. 2			Exp. 1	Exp. 2
PBS	2/10	5/8	7/18	39	2/2	0/5	2/7	28
Bacterin	10/10	6/6	16/16	100	0/10	0/6	0/16	0
Lsa77 +	5/10	4/8	9/18	50	4/5	0/4	4/9	44
Alum
p-value	0,17	0,5	0,36

The statistical analysis refers to Fisher’s exact test.p-values <0,05 were considered statistically significant.