|
| Study | Year | Tumor type | Kind/num. of analyzed samples | Methods | Expression status | Potential clinical significant |
|
| Nagahata, T. | 2005 | BC | 25 primary BC tissues | qRT-PCR | up | None |
|
| Tao, Q. | 2007 | LC | 18 pairs of human LC tissues and adjacent normal tissues; microarray with 186 LC tissues and 17 normal lung samples | qRT-PCR;
Microarray | down | None |
|
| Dairkee, S. H. | 2009 | BC | 50 pairs of cDNAs from matched BC and normal breast tissues; 147 invasive BC and 44 normal breast tissues | CPA;IHC | up | No association with clinical parameters and prognosis |
|
| Cheng, L. | 2012 | GC | 25 paired GC tissues and matched adjacent non-tumor tissues | Microarray;
qRT-PCR | up | None |
|
| Fujimoto, J. | 2012 | NSCLC | 31 NBE,24 COPD,26 COPD with cancer and 474 NSCLC tissnes;6 NSCLC and matched normal lung tissues | Microarray;
qRT-PCR | down | Positively associated with adenocarcinoma histology; highly suppressed in NCSSLC |
|
| Liu, S. L. | 2013 | OSCC | 60 paired primary OSCC and adjacent normal specimens | IHC | down | Inversely correlated with the malignant grade |
|
| Subrungruanga, I. | 2013 | ICC | 18 paired ICC and matched normal tissues | Microarray;
qRT-PCR | up | None |
|
| Zougman, A. | 2013 | CC | 347 CC specimens | Microarray | up | Positively correlated with tumor recurrence |
|
| Kume, H. | 2014 | CRC | 33 primary CRC and 16 colon polyps | LC-MS/MS | up | None |
|
| Lin, X. | 2014 | NSCLC | 129 paired NSCLC and adjacent normal tissues | IHC | down | None |
|
| Sokolenko, A. P. | 2014 | BC | 17 BC with BRCA1 mutation and 94 BRCA1 non-mutation tissues | qRT-PCR | down in BRCA1 mutation samples | Inversely correlated with BRCA1 mutation |
|
| Zheng, J. | 2014 | HCC | 106 HCC | qRT-PCR;WB;
IHC | up | Positively correlated with advanced TNM stage, high serum AFP, vascular invasion, tumor recurrence, DFS and OS |
|
| Liu, H. | 2016 | GC | 30 paired GC and adjacent normal tissues;106 GC samples | qRT-PCR;WB;
IHC | up | Positively associated with tumor size, diffuse type, serosal invasion,lymph node metastasis and OS |
|
| Zhou, H. | 2016 | Pancreatic cancer | 46 normal pancreatic tissues,145 primary pancreatic tumors and 61 metastatic tumors;203 samples pancreatic tumors | Microarray;
IHC | up | None |
|
| Jahny, E. | 2017 | PDAC | 435 PDAC and 209 non-cancerous pancreatic tissues | Microarray | up | None |
|
| Liu, S. | 2017 | HNSCC | 86 paired HNSCC and adjacent normal tissues | IHC | down | Positively associated with tumor differentiation |
|
| Zhang, L. | 2017 | CRC | 57 paired CRC and adjacent normal tissues | qRT-PCR | up | Positively associated with tumor grade |
|
