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BioMed Research International
Volume 2018, Article ID 1824790, 6 pages
Research Article

In Vitro Antidiabetic Effects and Antioxidant Potential of Cassia nemophila Pods

1Department of Zoology, Abdul Wali Khan University Mardan, Mardan, Pakistan
2Department of Botany, Abdul Wali Khan University Mardan, Mardan, Pakistan
3Department of Agriculture, Abdul Wali Khan University Mardan, Mardan, Pakistan
4Department of Chemistry, Abdul Wali Khan University Mardan, Mardan, Pakistan
5Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan
6Department of Biomedical Engineering and Sciences, SMME, National University of Science and Technology (NUST), H 12, Islamabad, Pakistan
7Division of Plant Biosciences, School of Applied Biosciences, College of Agriculture & Life Science, Kyungpook National University, Daegu, Republic of Korea

Correspondence should be addressed to Amjad Iqbal; moc.oohay@741labqidajma and InJung Lee;

Received 16 October 2017; Revised 8 December 2017; Accepted 19 December 2017; Published 23 January 2018

Academic Editor: Kazim Husain

Copyright © 2018 Gauhar Rehman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The antidiabetic and antioxidant potential of ethanolic extract of Cassia nemophila pod (EECNP) was evaluated by three in vitro assays, including yeast glucose uptake assay, glucose adsorption assay, and DPPH radical scavenging activity. The result revealed that the extracts have enhanced the uptake of glucose through the plasma membrane of yeast cells. A linear increase in glucose uptake by yeast cells was noticed with gradual increase in the concentration of the test samples. Moreover, the adsorption capacity of the EECNP was directly proportional to the molar concentration of glucose. Also, the DPPH radical scavenging capacity of the extract was increased to a maximum value of 43.3% at 80 μg/ml, which was then decreased to 41.9% at 100 μg/ml. From the results, it was concluded that EECNP possess good antidiabetic and antioxidant properties as shown by in vitro assays.