Protective Effects of Benzoic Acid, Bacillus Coagulans, and Oregano Oil on Intestinal Injury Caused by Enterotoxigenic Escherichia coli in Weaned Piglets

Table 6

Effects of dietary benzoic acid, bacillus coagulans, and oregano oil combined supplementation on inflammatory cytokines and sIgA concentrations in jejunal mucosa of weaned piglets challenged with Escherichia coli.

Items	CON	ETEC	AT	AB	AO	ABO	SEM	P1	P2^†
TNF-α (ng/L)	96.67	126.72	101.95	106.99	104.30	91.85	3.87	0.050	0.158
IL-1β (ng/L)	14.11	19.77	15.80	15.03	13.89	13.24	0.71	0.017	0.068
IL-6 (ng/L)	59.52	66.87	62.82	63.27	59.06	51.43	2.84	0.476	0.617
IL-10 (pg/ml)	163.08	134.96	175.23	168.09	176.50	‘167.63	7.17	0.186	0.488
sIgA (ug/ml)	46.30	36.92	45.98	50.05	48.61	57.48	2.14	0.025	0.131

TNF-α: tumor necrosis factor-α; IL: interleukin; sIgA: secretion immunoglobulin A.
^#Significantly different from CON group (p< 0.05). In the same row, different superscript letters show significant difference among ETEC-challenged groups (p< 0.05).
P1 was used to determine the response to ETEC challenge, CON v. ETEC.
^†P2 was used to determine the response to benzoic acid, bacillus coagulans, and oregano oil combined supplementation among ETEC-challenged piglets.