Research Article

Effects of Hemodialysis on Thiol-Disulphide Homeostasis in Critically Ill Pediatric Patients with Acute Kidney Injury

Table 3

Comparison of thiol/disulphide homeostatic parameters in hemodialysis group.

Pre-dialysisPost-dialysisp
Median (Q1-Q3)Median (Q1-Q3)

Native thiol (µmol/L)230.70 (182.63-293.60)294.45 (244.58-359.95) 0.003
Total thiol (µmol/L)256.45 (179.75-318-73)324.05 (276.00-410.63)0.003
Disulphide (µmol/L)13.50 (10.56-17.31)15.35 (12.92-21.15)0.021
Disulphide/native thiol (%)5.62 (4.44-7.88)6.15 (4.16-7.77)0.747
Disulphide/total thiol (%)5.08 (4.03-6.96)5.47 (3.84-6.72)0.778
Native thiol/total thiol (%)89.00 (85.50-91.83)89.70 (86.54-92.46) 0.841

<0.05 was considered significant for statistical analyses (Wilcoxon signed rank test).