In Vitro Neural Differentiation of Bone Marrow Mesenchymal Stem Cells Carrying the FTH1 Reporter Gene and Detection with MRI

Figure 4

Differentiation of MSCs into neuron-like cells. (a) Before induction, MSCs and MSCs-TFH1 exhibited a flat or spindle shape and no refraction. After induction, cells had enhanced transparency and thin and long processes that exhibited bipolar or multiple-polar expansion and connected to adjacent cells. (b) The neural differentiation rates between MSCs and MSCs-FTH1 did not exhibit significant differences (P>0.05). (c) The mean axonal lengths between Neurons and Neurons-FTH1 did not exhibit significant differences (P>0.05).

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