Review Article

Current Knowledge and Recent Advances of Right Ventricular Molecular Biology and Metabolism from Congenital Heart Disease to Chronic Pulmonary Hypertension

Figure 3

Right ventricular remodeling in congenital heart disease and pulmonary hypertension. βMHC: β-myosin heavy chain; HIF1α: hypoxia inducible factor 1α; VEGF: vascular endothelial growth factor; SERCA2a: sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2a; IVS: interventricular septum; αMHC: α-myosin heavy chain; FAO: fatty acids oxidation; RV-PA coupling: right ventricular-pulmonary arterial coupling; PVR: pulmonary vascular resistances; RV: right ventricular; iPAH: idiopathic pulmonary arterial hypertension; CTEPH: chronic thromboembolic pulmonary hypertension.