In Vitro Cytotoxicity and In Vivo Antimammary Tumor Effects of the Hydroethanolic Extract of Acacia seyal (Mimosaceae) Stem Bark

Figure 2

Effects of A. seyal extract on mammary gland tumors (a), volume of tumors (b), and tumors relative weight (c) after 20 weeks of treatment. NOR = normal control treated with water; DMBA = DMBA control treated with water; AS + DMBA = animals treated with the A. seyal hydroethanolic aqueous extract at the doses of 50, 150, and 300 mg/kg. TAM + DMBA = animals treated with tamoxifen (3.3 mg/kg); all groups excepting the normal group (NOR) received an intragastric dose of DMBA at the dose of 80 mg/kg. Data are represented as mean ± SEM (). Data are represented as mean ± SEM (). Data are represented as mean ± SEM (). , as compared to negative control. as compared to normal.

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