Enhancing Epitranscriptome Module Detection from m⁶A-Seq Data Using Threshold-Based Measurement Weighting Strategy

Figure 8

KEGG pathways enriched in epitranscriptome modules. Distinct pathways are enriched in different epitranscriptome modules. Interestingly and consistent with our understanding, insulin signaling pathway and nonalcoholic fatty liver disease are both enriched in epitranscriptome module M2 [48, 49] and axon guidance is enriched in module M1 [50]. Figure shows the top 10 most statistically enriched KEGG pathways in the identified epitranscriptome modules from DAVID [51]. Less terms are shown if there are less pathways enriched with significance level 0.05 using default setting of DAVID.