The Oncogenic Role of ARG1 in Progression and Metastasis of Hepatocellular Carcinoma

Table 2

ARG1 expression associated with the clinicopathological parameters in HCC.

clinicopathological parameters	n	ARG1 Low (n%)	ARG1 High (n%)	P
Gender
Male	74	59 (79.7)	15 (20.3)	0.713
Female	16	14 (87.5)	2 (12.5%)
Age (years)
<60	69	54 (78.3)	15 (21.7)	0.350
≥60	21	19 (90.5)	2 (9.5)
Tumor diameter (cm)
<5	44	40 (90.9)	4 (9.1)	0.020
≥5	46	33 (71.7)	13 (28.3)
Tumor envelope
Yes	47	40 (85.1)	7 (14.9)	0.311
No	43	33 (76.7)	10 (23.3)
Relapse
Yes	53	41 (77.4)	12 (22.6)	0.276
No	37	32 (86.5)	5 (13.5)
Cirrhotic nodule
Yes	78	64 (82.1)	14 (17.9)	0.853
No	12	9 (75.0)	3 (25.0)
Pathological grading
I-II	58	51(87.9)	7 (12.1)	0.026
III-IV	32	22(68.8)	10 (31.2)
DFS
<12	21	13 (61.9)	8 (38.1)	0.027
≥12	68	59 (86.8)	9 (13.2)
TB
<20μmol/L	74	60 (81.1)	14 (18.9)	1.000
≥20μmol/L	16	13 (81.3)	3 (18.7)
ALT
40U/L	41	38 (92.7)	3 (7.3)	0.010
≥40U/L	49	35 (71.4)	14 (28.6)
GGT
<40 U/L	24	24 (100.0)	0 (0)	0.014
≥40U/L	66	49 (74.2)	17 (35.8)
AFP
<400ng/ml	54	48 (88.9)	6 (11.1)	0.106
≥400ng/ml	33	25 (75.8)	8 (24.2)