Research Article
Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity
Table 1
Effects of resveratrol on blood pressure and heart rate in unanesthetized DM mice.
| Group | 1 month | 3 months | 6 months | HR (beats/min) | Diastolic BP (mm Hg) | Systolic BP (mm Hg) | HR (beats/min) | Diastolic BP (mm Hg) | Systolic BP (mm Hg) | HR (beats/min) | Diastolic BP (mm Hg) | Systolic BP (mm Hg) |
| Control | 637 ± 36 | 74.20 ± 3.27 | 105.32 ± 2.64 | 647 ± 35 | 75.10 ± 3.47 | 104.12 ± 2.34 | 640 ± 28 | 76.10 ± 2.45 | 106.13 ± 1.92 | Resveratrol | 645 ± 33 | 73.22 ± 3.85 | 102.29 ± 2.55 | 650 ± 32 | 74.42 ± 3.81 | 100.29 ± 2.35 | 646 ± 19 | 75.46 ± 2.25 | 102.16 ± 1.86 | DM | 646 ± 30 | 85.93 ± 2.41 | 115.26 ± 2.23 | 646 ± 29 | 86.93 ± 2.61 | 116.89 ± 2.37 | 636 ± 16 | 93.12 ± 3.25 | 121.75 ± 2.15 | DM/resveratrol | 636 ± 36 | 80.60 ± 3.82# | 104.23 ± 3.00# | 630 ± 40 | 79.65 ± 2.62# | 103.13 ± 3.11# | 629 ± 20 | 81.02 ± 1.63# | 108.13 ± 2.46# |
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Data are presented as means ± SEM. HR = heart rate; BP = blood pressure. versus control. versus DM group. |