Research Article

Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity

Table 1

Effects of resveratrol on blood pressure and heart rate in unanesthetized DM mice.

Group 1 month 3 months 6 months
HR
(beats/min)
Diastolic BP
(mm Hg)
Systolic BP
(mm Hg)
HR
(beats/min)
Diastolic BP
(mm Hg)
Systolic BP
(mm Hg)
HR
(beats/min)
Diastolic BP
(mm Hg)
Systolic BP
(mm Hg)

Control637 ± 3674.20 ± 3.27105.32 ± 2.64647 ± 3575.10 ± 3.47104.12 ± 2.34640 ± 2876.10 ± 2.45106.13 ± 1.92
Resveratrol645 ± 3373.22 ± 3.85102.29 ± 2.55650 ± 3274.42 ± 3.81100.29 ± 2.35646 ± 1975.46 ± 2.25102.16 ± 1.86
DM646 ± 3085.93 ± 2.41115.26 ± 2.23646 ± 2986.93 ± 2.61116.89 ± 2.37636 ± 1693.12 ± 3.25121.75 ± 2.15
DM/resveratrol636 ± 3680.60 ± 3.82#104.23 ± 3.00#630 ± 4079.65 ± 2.62#103.13 ± 3.11#629 ± 2081.02 ± 1.63#108.13 ± 2.46#

Data are presented as means ± SEM. HR = heart rate; BP = blood pressure. versus control. versus DM group.