Research Article

Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity

Table 2

Effects of resveratrol on cardiac dysfunction and heart rate in anesthetized DM mice (1 month).

GroupHR (beats/min)LVID (mm)IVS (mm)LVPW (mm)% EF (%)% FS (%)

Control496 ± 203.60 ± 0.230.71 ± 0.050.82 ± 0.189 ± 562 ± 4
Resveratrol459 ± 243.58 ± 0.320.72 ± 0.040.84 ± 0.1588 ± 4.058 ± 4.5
DM440 ± 263.59 ± 0.320.74 ± 0.050.86 ± 0.1778 ± 5.049 ± 5
DM/resveratrol465 ± 243.59 ± 0.380.73 ± 0.040.85 ± 0.1284 ± 555 ± 4

Data are presented as means ± SEM. LVID = LV end-diastolic diameter; LVPW = LV posterior wall; IVS = interventricular septum; FS = fractional shortening; EF = ejection fraction. versus control. versus DM group.