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BioMed Research International
Volume 2018, Article ID 2360107, 9 pages
Review Article

Percutaneous High Frequency Microwave Ablation of Uterine Fibroids: Systematic Review

1Department of Diagnostic and Interventional Radiology, San Paolo Hospital Medical School, University of Milan, Via A. Di Rudinì 8, 20142 Milan, Italy
2Unit of Obstetrics and Gynecology, Department of Biomedical and Clinical Sciences, ASST Fatebenefratelli Sacco, Hospital “L. Sacco”, University of Milan, 20157 Milan, Italy
3Department of Radiology, Cardarelli Hospital, 80123 Naples, Italy
4Unit of Obstetrics and Gynecology, Department of Health Sciences, San Paolo Hospital Medical School, University of Milan, Via A. di Rudinì 8, 20142 Milan, Italy

Correspondence should be addressed to Anna Maria Ierardi; ti.oohay@idrareima

Received 26 April 2017; Accepted 29 November 2017; Published 8 January 2018

Academic Editor: Tobias De Zordo

Copyright © 2018 Anna Maria Ierardi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Uterine fibroids are the most common benign pelvic tumor of the female genital tract and tend to increase with age; they cause menorrhagia, dysmenorrhea, pelvic pressure symptoms, back pain, and subfertility. Currently, the management is based mainly on medical or surgical approaches. The nonsurgical and minimally invasive therapies are emerging approaches that to the state of the art include uterine artery embolization (UAE), image-guided thermal ablation techniques like magnetic resonance-guided focused ultrasound surgery (MRgFUS) or radiofrequency ablation (RF), and percutaneous microwave ablation (PMWA). The purpose of the present review is to describe feasibility results and safety of PMWA according to largest studies available in current literature. Moreover technical aspects of the procedure were analyzed providing important data on large scale about potential efficacy of PMWA in clinical setting. However larger studies with international registries and randomized, prospective trials are still needed to better demonstrate the expanding benefits of PMWA in the management of uterine fibroids.