Incidence of Hippocampal Metastases: Laterality and Implications for Unilateral Hippocampal Avoiding Whole Brain Radiotherapy
Table 3
Presence of brain metastases (or their centre) within right and left hippocampus and hippocampal avoiding zones and laterality of hippocampal involvement.
within
within
within
P value
within
within
within
P value
H
left H
right H
HAZ
left HAZ
right HAZ
Patients (n=260) with edge of MTS
20 (7.7%)
12 (4.6%)
12 (4.6%)
47 (18.1%)
30 (11.5%)
27 (10.4%)
Patients (n=260) with more MTS
8
9
NS
22
20
p = 0.88
Patients (n=260) with centre of MTS
5 (1.9%)
3 (1.2%)
3 (1.2%)
25 (9.6%)
19 (7.3%)
12 (4.6%)
Patients (n=260) with more centre of MTS
2
2
NS
15
6
p = 0.07
Number of MTS (n=2595) with edge
28 (1.1%)
12 (0.5%)
16 (0.6%)
p = 0.57
86 (3.3%)
42 (1.6%)
44 (1.7%)
p = 0.91
Number of MTS (n=2595) with centre of MTS
7 (0.3%)
3 (0.1%)
4 (0.1%)
NS
41 (1.6%)
25 (0.9%)
16 (0.6%)
p = 0.21
MTS: metastasis, H: hippocampus, HAZ: hippocampus avoiding zone, NS: not specified, and p value close to 1.