Research Article
Predictive Role of QTc Prolongation in Carbon Monoxide Poisoning-Related Delayed Neuropsychiatric Sequelae
Table 2
Demographic and clinical data of patients with and without DNS.
| | Variables | Total
(N = 466) | DNS
(n = 62) | Non-DNS
(n = 404) | P value |
| | Male gender | 230 (49.4) | 35 (56.5) | 195 (48.3) | 0.275 | | Age (years) | 33 | 41 | 32 | 0.005 | | Psychiatric history | 82 (17.6) | 17 (27.4) | 65 (16.1) | 0.047 | | Pulse, beats/min | 100 | 96 | 100 | 0.346 | | Pulse > 100 beats/min | 216 (47.7) | 25 (41.0) | 191 (48.7) | 0.273 | | Glasgow Coma Score (GCS) | 15 | 14 | 15 | <0.001 | | GCS less than 9 | 62 (13.3) | 19 (30.6) | 43 (10.6) | <0.001 | | Triage scale | | | | 0.014 | | 1, resuscitation | 74 (15.9) | 18 (29.0) | 56 (13.9) | | | 2, emergent | 290 (62.2) | 33 (53.2) | 257 (63.6) | | | 3, urgent | 94 (20.2) | 9 (14.5) | 85 (21.0) | | | 4/5 less urgent/not urgent | 8 (1.7) | 2 (3.2) | 6 (1.5) | | | Transferred from outside institution | 223 (47.9) | 37 (59.7) | 186 (46.0) | 0.056 | | Attempted suicide | 190 (40.8) | 42 (67.7) | 148 (36.6) | <0.001 | | Source of CO poisoning | | | | <0.001 | | Charcoal burning | 196 (42.1) | 45 (72.6) | 151 (37.4) | | | Inappropriately ventilated gas heating appliances | 238 (51.1) | 13 (21.0) | 225 (55.7) | | | Others | 32 (6.9) | 4 (6.5) | 28 (6.9) | | | Concomitant use with tranquilizer | 63 (13.5) | 15 (24.2) | 48 (11.9) | 0.015 | | Transient loss of consciousness | 292 (62.7) | 55 (88.7) | 237 (58.7) | <0.001 | | Duration of loss of consciousness | | | | <0.001 | | < 6 hours | 210 (71.9) | 25 (45.5) | 185 (78.1) | | | 6-12 hours | 28 (9.6) | 5 (9.1) | 23 (9.7) | | | 13-24 hours | 20 (6.8) | 13 (23.6) | 7 (3.0) | | | > 24 hours | 16 (5.5) | 10 (18.2) | 6 (2.5) | | | > 48 hours | 18 (6.2) | 2 (3.6) | 16 (6.8) | | | Leukocytosis | 245 (56.5) | 43 (74.1) | 202 (53.7) | 0.004 | | Metabolic acidosis | 67 (19.1) | 9 (19.6) | 58 (19.1) | 1.000 | | COHb, % | 10.1 | 7.4 | 10.9 | 0.095 | | Troponin I, ng/mL | 0.20 | 0.93 | 0.14 | 0.001 | | Evidence of myocardial injury | 64 (18.0) | 21 (42.9) | 43 (14.0) | <0.001 | | Time from CO exposure to ED (hours) | 4.0 | 9.8 | 4.0 | <0.001 | | Time from CO exposure to ECG recording (hours) | 5.1 | 8.3 | 4.8 | <0.001 | | QTc prolongation | 149 (42.1) | 37 (69.8) | 112 (37.2) | <0.001 | | Brain CT imaging study at first medical institution | 131 (28.1) | 40 (64.5) | 91 (22.5) | <0.001 | | HBOT | 279 (59.9) | 47 (75.8) | 232 (57.4) | 0.008 | | Number of HBOT sessions | 3 | 4 | 2 | <0.001 | | Length of hospital stay (days) | 1 | 5 | 1 | <0.001 | | ICU stay (days) | 26 (5.6) | 10 (16.1) | 16 (4.0) | 0.001 | | Lucid interval, duration from exposure to DNS (days) | NA | 10 | NA | NA |
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Continuous data were expressed as median ( and percentiles); categorical data were presented as frequency (proportion). |
