Research Article

Standardized Duplex Ultrasound-Based Protocol for Early Diagnosis of Transplant Renal Artery Stenosis: Results of a Single-Institution Retrospective Cohort Study

Table 3

Flow-chart detailing the study design. TRAS = transplant renal artery stenosis.

Patients undergoing kidney transplantation from July 1991 at Careggi University Hospital  
()

Patients eligible for the standardized ECD- based follow-up protocol for early detection of TRAS (started on January 1998)  
(, 85%)
Patients undergoing KT from 1991 to 1998 excluded due to lack of standardized follow- up protocols for diagnosis of TRAS  
(, 15%)

Patients enrolled in the standardized follow-up protocol with complete clinical data available  
(, 77%)
Patient excluded due to the following  
(i) Any medical or surgical complications in the postoperative period
(ii) Unavailable clinical data
(iii) Lack of follow-up data
(, 23%)

Patients enrolled in the study undergoing regular follow-up at our Institution  
(Study population)  
(, 97%)
Patients with ECD diagnosis of transplant renal artery kinking (TRAK) excluded from the study  
(, 3%)

Patients with clinical or ECD suspicion of TRAS undergoing diagnostic angiography  
(, 10%)
Patients continuing the Protocol Strategies according to the specific risk categories  
(Table 2)
(, 90%)

Patients diagnosed with TRAS  
(, 95%)
Patients with no evidence of TRAS, of which 1 TRAK, continuing the regular follow-up protocol  
(, 5%)

Patients with TRAS < 50% continuing regular follow-up protocol  
(; 2%)
Patients with TRAS of 50–70% with a peak systolic pressure gradient across the stenosis of <20 mmHg undergoing PTA only  
(; 5%)
Patients with TRAS > 70% with a peak systolic pressure gradient across the stenosis of >20 mmHg undergoing PTA + Stenting  
(; 93%)
Patients undergoing diagnostic angiography for suspicion of TRAS during follow-up  
(, 14%)

Patients with re-TRAS treated with re-PTA + stenting  
()
Patients with no evidence of TRAS continuing the regular follow-up protocol  
()