Standardized Duplex Ultrasound-Based Protocol for Early Diagnosis of Transplant Renal Artery Stenosis: Results of a Single-Institution Retrospective Cohort Study
Table 3
Flow-chart detailing the study design. TRAS = transplant renal artery stenosis.
Patients undergoing kidney transplantation from July 1991 at Careggi University Hospital ()
Patients eligible for the standardized ECD- based follow-up protocol for early detection of TRAS (started on January 1998) (, 85%)
Patients undergoing KT from 1991 to 1998 excluded due to lack of standardized follow- up protocols for diagnosis of TRAS (, 15%)
Patients enrolled in the standardized follow-up protocol with complete clinical data available (, 77%)
Patient excluded due to the following (i) Any medical or surgical complications in the postoperative period (ii) Unavailable clinical data (iii) Lack of follow-up data (, 23%)
Patients enrolled in the study undergoing regular follow-up at our Institution (Study population) (, 97%)
Patients with ECD diagnosis of transplant renal artery kinking (TRAK) excluded from the study (, 3%)
Patients with clinical or ECD suspicion of TRAS undergoing diagnostic angiography (, 10%)
Patients continuing the Protocol Strategies according to the specific risk categories (Table 2) (, 90%)
Patients diagnosed with TRAS (, 95%)
Patients with no evidence of TRAS, of which 1 TRAK, continuing the regular follow-up protocol (, 5%)
Patients with TRAS < 50% continuing regular follow-up protocol (; 2%)
Patients with TRAS of 50–70% with a peak systolic pressure gradient across the stenosis of <20 mmHg undergoing PTA only (; 5%)
Patients with TRAS > 70% with a peak systolic pressure gradient across the stenosis of >20 mmHg undergoing PTA + Stenting (; 93%)
Patients undergoing diagnostic angiography for suspicion of TRAS during follow-up (, 14%)
Patients with re-TRAS treated with re-PTA + stenting ()
Patients with no evidence of TRAS continuing the regular follow-up protocol ()