Effect of Chronic Kidney Disease on Changes in Vasopressin System Expression in the Kidney Cortex in Rats with Nephrectomy

Table 1

Biochemical parameters in the urine.

Parameters	CN	N1/2	N2/3	N5/6
	(n=7)	(n=7)	(n=6)	(n=8)
urine volume (ml/24h)	8,53 ± 0,54	14,21 ± 0,99^##	15,90 ± 0,58^&	25,10 ± 3,01
osmolarity (mOsmol/kgH2O)	1786 ± 84,44	2004.0 ± 99.9^###@	1589.8 ± 55.2^&	1191.7 ± 108.3
urea (mg/ml)	7805.8 ± 558.4	5552.9 ± 420.7^###	5235.0 ± 464.9^&&&	1331.3 ± 162.8
sodium (mmol/l)	92.1 ± 6.3	86.9 ±5.0^###	69.6 ± 7.6	53.0 ± 8.5
creatinine (mg/dl)	110.8 ± 8.1	95.7 ± 5.7^###	106.0 ± 12.0^&&&	29.5 ± 6.0
protein (mg/dl)	148.7 ± 8.0	345.1 ± 24.9	1780.0 ± 577.4	705.9 ± 101.5
protein/creatinine	1.4 ± 0.1	3.7 ± 0.4	19.6 ±7.7	65.3 ± 33.5

Biochemical parameters of urine. CN: control group; N1/2: 1/2 nephrectomy group; N2/3:2/3 nephrectomy group; N5/6: 5/6 nephrectomy group. Means ± SE are shown. Significant difference between N5/6 and CN groups; ^#significant difference between N5/6 and N1/2 groups; ^&significant difference between N5/6 and N2/3 groups; ^@significant difference between N2/3 and N1/2 groups; significant difference between N2/3 and CN groups; significant difference between N1/2 and CN groups. P<0.01; P<0.001; ^#P<0.05; ^###P<0.001; ^&P<0.05; ^&&&P<0.001; ^@P<0.05; P<0.05; P<0.01; P<0.01.