Impaired Gut Epithelial Tight Junction Expression in Hemodialysis Patients Complicated with Intradialytic Hypotension

Figure 1

Immunohistochemical expression of claudin-1 in the colon mucosa of patients with non-CKD (control) (a) or advanced CKD (b) HD patients with hypotension (c). There was no significant difference in claudin-1 expression between non-CKD and CKD patients (red arrows). A significant decrease in claudin-1 staining extent and intensity was only seen in HD patients (blue arrows) (c).

(a)

(b)

(c)