Microarray-Based Detection and Clinical Evaluation for Helicobacter pylori Resistance to Clarithromycin or Levofloxacin and the Genotype of CYP2C19 in 1083 Patients

Figure 2

Visible detection of CYP2C192, CYP2C193, 23S rRNA, and gyrA (positive and negative controls). (a) Wild genotype of CY2C192 and CY2C193. (b) Mutation genotype of CY2C192 and CY2C193. (c) Wild at position 2142 and 2143 of 23S rRNA, wild genotype T at Asn-87, and mutant genotype GG at Asp-91 of gyrA. (d) Mutant at position 2142 and wild at position 2143 of 23S rRNA, wild genotype C at Asn-87 and wild genotype GA at Asp-91 of gyrA. (e) Wild at position 2142 and mutant at position 2143 of 23S rRNA, mutant genotype G at Asn-87, and wild genotype GA at Asp-91 of gyrA. (f) Mutant at position 2142 and 2143 of 23S rRNA, wild genotype T at Asn-87, and wild genotype GA at Asp-91 of gyrA. (g) Wild at position 2142 and 2143 of 23S rRNA, mutant genotype A at Asn-87, and mutant genotype AA at Asp-91 of gyrA. (h) Standard strain 26695 of H. pylori.

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