Extracellular Vesicles: A New Perspective in Tumor Therapy

Figure 1

Integrins are a large family of heterodimeric transmembrane receptors that mediate cell attachment to other cells or to the extracellular matrix via interactions with proteins such as fibronectin and collagen. Integrins are heterodimers composed of an α and a β subunit, and they play important roles in many physiological and pathological processes. Yuwen et al. found that exosomal integrin α6β4 and integrin α6β1 were closely linked to lung metastasis, and integrin αVβ5 was closely linked to liver metastasis.