Aerobic Interval Training Regulated SIRT3 Attenuates High-Fat-Diet-Associated Cognitive Dysfunction

Figure 3

AIT improves hippocampal SIRT3-MnSOD in HFD mice. (a) Body mass of each group’s mice. (b) Random-fed blood glucose of each group’ mice. (c) Adipose mass of each group’ mice. (d) Representative immunoblots of mitochondria SIRT3 and MnSOD were detected by Western blots. (e) The acetylation level of mitochondria protein was examined by immunoblots. (f) The acetylation of MnSOD was examined by coimmunoprecipitation. (g) MnSOD activity. (h) ROS levels in hippocampus. versus Con; versus HFD. Values are means ± SEM, independent experiments.

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